Global Survey Highlights Variability in Bone Metabolism Biomarker Measurements Across Countries

Just now September 30, 2026 1 min read 📰 Medical Xpress

📋 Key Takeaway

A global survey by the IOF and IFCC revealed significant variations in laboratory practices for measuring bone status indices across 41 countries, including Iran. This variability hampers data sharing and standardization of tests, which could impact clinical practices in Iran. The findings highlight the need for improved standardization in medical testing.

Researchers from the International Osteoporosis Foundation (IOF) and International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) Joint Committee on Bone Metabolism published a study examining self-reported practices among laboratories that measure bone status indices (BSIs) in blood tests. Published Aug. 7, 2026, in Clinical Chemistry and Laboratory Medicine, the study collected 231 responses from 41 countries. The findings show substantial variation in global BSI laboratory practices that limits data sharing, test standardization and clinical impact.