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Enhanced DNA Exchange in Starving Bacteria Could Inform Adaptation Strategies

Just now October 1, 2026 1 min read 📰 Phys.org
📋 Key Takeaway

Researchers from ISTA discovered that E. coli bacteria can exchange DNA through bacteriophages and CRISPR-Cas immunity during starvation, enhancing genetic adaptation. This process, akin to primitive sexual reproduction, may be crucial for bacterial survival in changing environments. The findings, published in Molecular Biology and Evolution, highlight the adaptability of organisms under stress, which could have implications for understanding biological resilience in various contexts, including those relevant to Iran.

How do bacteria adapt when resources run low? ISTA researchers have found that, under starvation stress, E. coli can use bacteriophages and CRISPR-Cas immunity to transfer and incorporate DNA, accelerating genetic reshuffling. The process resembles a primitive form of sexual reproduction and may help bacterial populations adapt to changing conditions. The findings were published in Molecular Biology and Evolution.

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