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Immunotherapy Combination Significantly Improves Survival for Small Cell Lung Cancer Patients

Just now October 26, 2026 1 min read 📰 Medical Xpress
📋 Key Takeaway

A clinical trial demonstrated that the combination of tarlatamab and durvalumab significantly improves survival rates for patients with extensive-stage small cell lung cancer. This advancement in cancer treatment could have implications for healthcare advancements in Iran, particularly in oncology.

In patients with extensive-stage small cell lung cancer (ES-SCLC), tarlatamab, a bispecific T-cell engager, plus durvalumab as first-line maintenance therapy extended median overall survival by more than eight months, more than tripled progression-free survival and reduced the risk of death by 58% compared to durvalumab alone, according to results of the phase 3 open-label, multicenter, randomized DeLLphi-305 study.

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