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Iran's Leader: The U.S. is the one that should leave the region, not the Islamic Republic

Jun 6, 2026 June 6, 2026 4 min read 📰 Radio Farda
📋 Key Takeaway

Iran's Supreme Leader Ayatollah Khamenei declared that the U.S. is responsible for regional instability and should withdraw from the Middle East, not the Islamic Republic. He emphasized Iran's resilience against economic warfare and warned regional countries against confronting Iran. This statement comes amid rising tensions following missile attacks in Syria and ongoing discussions about U.S. sanctions.

🔍 Quick Context Guide
💡 Bottom Line: Khamenei's remarks signal Iran's defiance against U.S. and Israeli actions.

👥 Key Players

Ali Khamenei (علی خامنه‌ای) QUOTED
Supreme Leader
""the era of impunity is over""
James Mattis QUOTED
U.S. Defense Secretary
""he can imagine how this conflict might start but cannot guess how far and where it might escalate.""
Abbas Araqchi (عباس عراقچی) QUOTED
Deputy Foreign Minister
""we have prepared options for all scenarios and have special measures in place.""
Donald Trump (دونالد ترامپ) QUOTED
Former U.S. President
""if the 'catastrophic flaws and deficiencies' of the JCPOA... are not corrected, he will not extend the suspension of Iran's sanctions.""
Avigdor Lieberman QUOTED
Israeli Defense Minister
""they will not hesitate to respond to the actions of the Islamic Republic, even in the form of direct attacks on Iranian territory.""
U.S. Secretary of State ACTOR
U.S. Secretary of State
"Traveled to Saudi Arabia, Jordan, and Israel shortly after his appointment."

⚡ Actions

Ali Khamenei ANNOUNCE United States
""the one that should leave the region is the U.S., not the Islamic Republic.""
Confidence: 90%
Ali Khamenei WARN regional countries
""if they confront the Islamic Republic, they will certainly suffer defeat.""
Confidence: 90%
U.S. Government DESIGNATE Iran
""the economic war room against the Islamic Republic is the U.S. Treasury Department.""
Confidence: 80%

📰 What Happened

Khamenei asserts the U.S. should leave the region, blaming it for regional instability and warning against confrontation.

  • Ali Khamenei announce United States
  • Ali Khamenei warn regional countries
  • U.S. Government designate Iran

💡 Why It Matters

🇮🇷 For Iran: Because Khamenei's statements reinforce Iran's stance against U.S. influence in the region.
🌍 Regional: Because tensions between Iran and Israel could escalate into broader conflict.
🌐 International: Because U.S. sanctions and military presence are central to Iran's regional strategy.

📚 Background

Khamenei's remarks signal Iran's defiance against U.S. and Israeli actions.

📝 Key Evidence

""war, insecurity, and bloodshed in the region are caused by the U.S. presence.""
→ Indicates Khamenei's view on U.S. influence causing regional instability.
""the U.S. does not want to bear the costs of confronting the Islamic Republic.""
→ Highlights U.S. reluctance to engage militarily with Iran.
📡 Source: STATE MEDIA
📊 Confidence: 80%
Radio Farda is known for its critical stance towards the Iranian government.

Ayatollah Ali Khamenei, the leader of the Islamic Republic, stated on Monday that "war, insecurity, and bloodshed in the region" are caused by the U.S. presence, and "the one that should leave the region is the U.S., not the Islamic Republic." In remarks made to workers and entrepreneurs on Labor Day, Khamenei also emphasized that the "era of impunity" is over, without directly referencing recent events in Syria, including an alleged Israeli attack on a military base in Syria where several Iranians were reportedly killed. He compared Donald Trump to other U.S. presidents, labeling them as "immoral and ridiculous," and stated that Americans know that "if they engage in military conflict with Iran, they will suffer significantly more damage." The missile attack on Sunday night on targets in Syria, including a storage facility for ground-to-ground missiles, left at least 26 dead, but while sources like the Syrian Observatory for Human Rights claim that most of the casualties were Iranian, Iranian media have denied this based on informed sources. Iran's presence near Israel's borders in Syria has raised concerns for Israel, and Israeli officials have emphasized that they will not hesitate to respond to the actions of the Islamic Republic, even in the form of direct attacks on Iranian territory. Recently, U.S. Defense Secretary James Mattis, in a congressional meeting and during a visit with his Israeli counterpart Avigdor Lieberman, did not rule out the possibility of conflict between Israel and Iran over Iran's military presence in Syria, adding that "he can imagine how this conflict might start but cannot guess how far and where it might escalate." In recent days, the U.S. Secretary of State traveled to Saudi Arabia, Jordan, and Israel shortly after his appointment, with reports indicating that the main goal of this trip was to garner support from America's regional allies for potential new sanctions against Iran. However, on Monday, the Iranian leader stated that the U.S. does not want to bear the costs of confronting the Islamic Republic and is seeking to "provoke some of the less informed governments in the region" and "create discord and conflict within the region." He warned regional countries that "if they confront the Islamic Republic, they will certainly suffer defeat." Khamenei also emphasized that the U.S. government is currently focusing on an economic and cultural war against the Islamic Republic, stating that "the economic war room against the Islamic Republic is the U.S. Treasury Department." He added that to counter this "economic war," reliance on domestic capabilities and support for domestic products is essential. Khamenei stated that he does not believe in severing ties with the world but emphasized that reliance should not be placed outside the borders. He reminded that "the world is not just the U.S. and a few European countries" and that connections should be made with various countries. Last fall, the U.S. President tasked the Treasury Department with designing new sanctions against Iran, especially concerning the Islamic Revolutionary Guard Corps, as part of his new strategy towards Iran. Since then, the U.S. has repeatedly added various individuals and entities to its sanctions list in connection with Iran's missile program and cyber activities attributed to Iran. Recently, as the three European powers involved in the JCPOA proposed sanctions regarding Iran's missile program and regional presence to the European Union to encourage the U.S. to remain in the nuclear deal, the U.S. has also sought sanctions from other countries against Iran's missile program. Meanwhile, the expiration of Donald Trump's deadline regarding the reform of the JCPOA may mean the reinstatement of some of the sanctions against Iran that the U.S. President suspended periodically under the nuclear agreement. Trump has stated that if the "catastrophic flaws and deficiencies" of the JCPOA, such as its exclusion of the missile program, are not corrected, he will not extend the suspension of Iran's sanctions and may even withdraw from it. In response, Iran, which has previously stated that it has various options in response to a potential U.S. withdrawal from the JCPOA, indicated through Abbas Araqchi, the Deputy Foreign Minister, that whether or not the U.S. exits the JCPOA, the continuation of this situation will not be tolerable. He told ISNA that they have prepared options for all scenarios and have special measures in place, and any possibility, including a return to pre-JCPOA conditions, could exist.

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Translated from the original and edited for English readers. View original source →

Translation confidence: 85%

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